- Sapphire berry
- Sappiness
- Saprophagous
- Saptharshis
- Sarcastic
- Sarco
- Sarcoderm
- Sarcoma
- Sardonyx
- Sarong
- Sarp-pointed
- Sarsaparilla
- Sassafras
- Sassy
- Satanism
- Sateless
- Satellite
- Sathapatha brahmanam
- Satiation
- Satiety
- Satin
- Satire
- Satirize
- Satrap
- Satuagraha
- Saturated solution
- Saturday
- Saturns rings
- Satyriasis
- Sauna
- Sauropsida
- Saute
- Savage
- Saw-tooth
- Savagery
- Savannah
- Save once face
- Save somenes neck
- Save someones neck
- Saving clause
- Saviour
- Savoir faire
- Savory
- Savoulesls
- Savoy
- Sawn
- Sawpit
- Sawyer
- Saxatile
- Say for certain
- Say for oneself
- Saying
- Sbc
- Sblood
- Scabble
- Scabrous
- Scabrousness
- Scalawag
- Scalding tears
- Scale
- Scale down
- Scale-insect
- Scalene
- Scaler
- Scales
- Scalloped
- Scallywag
- Scalpel
- Scamble
- Scamp
- Scandalisation
- Scandinavian
- Scanty
- Scapular
- Scarabee
- Scare away
- Scare out
- Scarf-joint
- Scarification
- Scarless
- Scavenge
- Scenery
- Scenically
- Scent
- Scent treachery
- Scentless
- Scepticism
- Sceptral
- Scheduled
- Scheme against
- Schism
- Schizoid
- Schizophrenia
- Schlemiel
- Schmaltz
- Schmo
- Schmuck
- Schnapps
- Scholarliness
- School